Sophie AKC, OFA, DNA Toy Poodle

Our AKC Toy Poodle Sophie, OFA, DNA

One of our Dam / Moms is our little girl named Sophie. Her name is deriving from the beautiful Greek Sophie, meaning “wisdom.” It's the number-one human name in Scotland and the Netherlands.  She is a gorgeous purebred AKC Toy poodle that only weighs 8lbs, We have had her since she was a puppy.  Her parents were perfect size as well.  Her Mom only weighed 9lbs and her Dad only weighed 5.4lbs.
Sophie is fully DNA Certified with Embark.

They have partnered with the Cornell University College of Veterinary Medicine, the leading veterinary school in the country and I feel they are the most comprehensive canine DNA testing available anywhere.  Sophie also has been certified for his OFA clearances and is PRA clear. He and has a gorgeous thick, dark red coat with dark pigment skin and has a 
calm sweet personality.

She is more than just a pet...She is a member of our family.

Our Sophie has been tested by Embark and he is clear on Embark's 210 DNA clinical traits.


Sophie has also been tested clear for 6 genetic conditions that are common in her breed which are listed below.

Von Willebrand Disease Type I

Von Willebrand Disease (vWD) is a type of coagulopathy, a disorder of blood clotting. vWD is characterized into three types based on clinical severity, serum levels of vWF, and vWF multimer composition. Dogs with Type I vWD have low vWF levels, normal multimer composition, and variable clinical signs.
Seen in small or Toy Poodles but not our Sophie.


Congenital Macrothrombocytopenia

This is a benign disorder of platelet production that leads to abnormally large, sparse platelets.
Seen in small or Toy Poodles but not our Sophie.


Progressive Retinal Atrophy, prcd

PRA-prcd is a retinal disease that causes progressive, non-painful vision loss in many breeds. The retina contains cells, called photoreceptors, that collect information about light and send signals to the brain. There are two types of photoreceptors: rods, for night vision and movement, and cones, for day vision and color. This type of PRA leads to early loss of rod cells, leading to night blindness before day blindness.
Seen in small or Toy Poodles but not our Sophie.


GM2 Gangliosidosis

A lysosome is a structure within the cell that digests and removes waste. When the lysosome cannot recycle waste properly, the waste accumulates and causes the cell to die. This form of lysosomal storage disease (gangliosidosis) is caused by buildup of a fatty substance known as ganglioside, especially in cells of the nervous system.
Seen in small or Toy Poodles but not our Sophie.


Neonatal Encephalopathy With Seizures, NEWS

ATF2 is a DNA-binding protein known to mediate the cellular response to DNA damage. It has been linked to a variety of diseases including NEWS; notably, mice deficient in ATF2 have neurologic deficits similar to NEWS puppies.
Seen in small or Toy Poodles but not our Sophie.



Skeletal Dwarfism (Poodle Variant)
Osteochondrodysplasia, Skeletal Dwarfism

As a fetus, most of the bones of the body actually start as cartilage models of themselves. Over time, the cartilage is replaced with the bones that you (and your dog) are born with. Dogs affected with osteochondrodysplasia have a mutation in the SLC13A1 gene, which codes for a protein that transports minerals into the developing bone. Defects in this gene disrupt the cartilage to bone transition, leading to inappropriate skeletal development.
Seen in small or Toy Poodles but not our Sophie.



They are more than just pets...They are member's of our family.
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